Description
CD55 Antibody [143-30] (FITC) | 99-554 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: PHA activated peripheral blood mononuclear cells
Research Area: Signal Transduction
Tested Application: Flow
Application: CD55 Antibody [143-30] for use in flow cytometry, immunohistochemistry, and western blotting assays.
Specificiy: CD55
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [143-30]
Isotype: IgG1
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: DAF, decay accelerating factor
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD55, also known as decay accelerating factor (DAF) , is an 80 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters.