CD72.1 Antibody [10.1.D2] (Biotin) | 98-842

CD72.1 Antibody [10.1.D2] (Biotin) | 98-842 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Mouse

Homology: N/A

Immunogen: DBA/2 mouse spleen cells

Research Area: Immunology, Signal Transduction

Tested Application: Flow

Application: CD72.1 Antibody [10.1.D2] for use in flow cytometry and immunoprecipitation assays.

Specificiy: CD72.1

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [10.1.D2]

Isotype: IgG2b

Conjugate: Biotin

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Lyb-2.1, CD72a, Lyb-2a

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Murine CD72.1 (Lyb-2.1) , a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.