CD74 Polyclonal Antibody | E-AB-40347

CD74 Polyclonal Antibody | E-AB-40347 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD 74, CD74, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 antigen, CD74 molecule, CD74 molecule, major histocompatibility complex, class II invariant chain, CLIP, DHLAG, Gamma chain of class II antigens, HG2A, HLA class II histocompatibility antigen gamma chain, HLA DR antigens associated invariant chain, HLA DR gamma, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, HLADG, HLADR antigens associated invariant chain, Ia antigen associated invariant chain, Ia antigen-associated invariant chain, Ia associated invariant chain, Ia gamma, Ii, Invariant polypeptide of major histocompatibility complex class II antigen associated, la-gamma, Major histocompatibility complex class II invariant chain, MHC HLA DR gamma chain, MHC HLA-DR gamma chain, p33, p35, Protein 41

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology

Background: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration: 0.95 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human HLA class II histocompatibility antigen gamma chain protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:500-1:1000 IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 33, 26, 18 kDa

Molecular Weight(Observed): 35 kDa