CD79B polyclonal Antibody | BS60825

CD79B polyclonal Antibody | BS60825 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:204

Background: CD79 (also designated Ig α/Ig β) is a heterodimer composed of α chains, designated CD79A or MB-1, and β chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif,which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Storage & Stability: Store at 4°C short term. Aliquot and store at -24°C long term. Avoid freeze-thaw cycles.

Specificity: CD79B polyclonal Antibody detects endogenous levels of CD79B protein.

Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD79b; CD79B; B29; IGB

Immunogen: A synthetic peptide corresponding to residues in Human CD79B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 99% (by SDS-PAGE) .

Pathway: