CD8 Antibody [RAVB3] | 32-134

CD8 Antibody [RAVB3] | 32-134 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3) .

Research Area: Immunology,

Tested Application: E, WB

Application: Western Blot:1:500 - 1, 000
ELISA:Determining optimal working dilutions by titration test.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A affinity chromatography.

Clonality: Monoclonal

Clone: RAVB3

Isotype: IgG1

Conjugate: Unconjugated

Physical State: N/A

Buffer: Purified antibody in PBS containing 0.03% sodium azide.

Concentration: N/A

Storage Condition: CD8 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: MALCD8, MAL, p32, Leu2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.