CD8b Antibody [341] | 76-659

CD8b Antibody [341] | 76-659 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Rat

Homology: N/A

Immunogen: N/A

Research Area: Immunology, Functional Assays

Tested Application: Flow, Func

Application: N/A

Specificiy: The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Clonality: Monoclonal

Clone: 341

Isotype: Mouse IgG1, kappa

Conjugate: Unconjugated

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.

Alternate Name: Cd8b1, Cd8b

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.