Cdc25B (K349) polyclonal Antibody | BS1523

Cdc25B (K349) polyclonal Antibody | BS1523 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: IHC IF

Application Range: IHC: 1:50~1:200 IF: 1:50~1:200

Background: The activity of cyclin dependent kinases in cell cycle is regulated by the phosphorylation status, which is controlled by the antagonistic action of wee 1 kinase and Cdc25 phosphatases. Three Cdc25 genes are present in human cells: Cdc25A, Cdc25B and Cdc25C. Cdc25A and Cdc25B are expressed throughout the cell cycle, with peak expression in G1 for Cdc25A and in both G1 S phase and G2 for Cdc25B. Cdc25C is mainly expressed in G2 phase.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CDC25B (K349) polyclonal Antibody detects endogenous levels of CDC25B protein.

Molecular Weight: ~ 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: M-phase inducer phosphatase 2; Dual specificity phosphatase Cdc25B; CDC25B; CDC25HU2

Immunogen: Synthetic peptide, corresponding to amino acids 320-370 of Human Cdc25B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: