Cdc42EP2 (L24) polyclonal Antibody | BS3830

Cdc42EP2 (L24) polyclonal Antibody | BS3830 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cdc42EP2 (L24) polyclonal Antibody detects endogenous levels of Cdc42EP2 protein.

Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cdc42 effector protein 2; Binder of Rho GTPases 1; CDC42EP2; BORG1; CEP2

Immunogen: Synthetic peptide, corresponding to amino acids 1-50 of Human Cdc42EP2.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A