CDH23 Antibody | 19-497

CDH23 Antibody | 19-497 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-270 of human CDH23 (NP_001165402.1) .

Research Area: Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:200 - 1:1000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: B cells

Positive Control 3: Mouse liver

Positive Control 4: Mouse testis

Positive Control 5: Mouse heart

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 52kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDH23, cadherin-like 23, DFNB12, DKFZp434P2350, FLJ00233, FLJ36499, KIAA1774, KIAA1812, MGC102761, USH1D, USH1H, OTTHUMP00000044780, cadherin 23, cadherin related 23, cadherin-23, otocadherin, UNQ1894/PRO4340

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.