CDk1 polyclonal Antibody | BS90278

CDk1 polyclonal Antibody | BS90278 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, mouse, rat

Application: WB ICC IHC FC

Application Range: WB:1:500 ICC:1:200 IHC:1:200 FC:1:100-1:200

Background: Cdk1 is a small protein (approximately 34 kilodaltons), and is highly conserved. Cdk1 is comprised mostly by the bare protein kinase motif, which other protein kinases share. Cdk1, like other kinases, contains a cleft in which ATP fits. When bound to its cyclin partners, Cdk1 phosphorylation leads to cell cycle progression. Given its essential role in cell cycle progression, Cdk1 is highly regulated. Most obviously, Cdk1 is regulated by its binding with its cyclin partners. Cyclin binding alters access to the active site of Cdk1, allowing for Cdk1 activity; furthermore, cyclins impart specificity to Cdk1 activity. At least some cyclins contain a hydrophobic patch which may directly interact with substrates, conferring target specificity. Furthermore, cyclins can target Cdk1 to particular subcellular locations.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CDk1 polyclonal Antibody detects endogenous levels of CDk1 protein.

Molecular Weight: 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CDK1, Cdc 2, Cdc2, CDC28A, CDK 1, CDK1, CDK1, CDKN1, CELL CYCLE CONTROLLER CDC2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, Cell Divsion Cycle 2 Protein, Cyclin Dependent Kinase 1, Cyclin-dependent kinase 1, DKFZp686L20222, MGC111195, p34 Cdk1, p34 protein kinase, P34CDC2,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: