CDK19 Antibody | 16-434

CDK19 Antibody | 16-434 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1) .

Research Area: Apoptosis, Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: DU145

Positive Control 2: U-87MG

Positive Control 3: A-549

Positive Control 4: HeLa

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 57kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDC2L6, KIAA1028, death-preventing kinase, cyclin-dependent kinase (CDC2-like) 11, cell division cycle 2-like 6 (CDK8-like) , CDK8-like cyclin-dependent kinase, CDK11, bA346C16.3, CDC2L6

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.