CDK2AP1 Protein, Human Recombinant | P1630

Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), a growth suppressor that negatively regulates CDK2 activity, has been implicated in various types of cancer. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation.

P1630 | CDK2AP1 Protein, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2

Alternates names: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2

Taglines:

NCBI Gene ID #: 8099

NCBI Gene Symbol: O14519

Gene Source: Human

Accession #: NP_004633, O14519

Recombinant: FALSE

Source: E.coli

Purity by SDS-PAGE: ≥ 95% by SDS-PAGE

Assay:

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Binding Capacity:

Unit Definition:

Molecular Weight: 16.6 kDa

Concentration:

Appearance: Sterile Filtered colorless solution

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: 1-152 aa

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans