CDK3 polyclonal Antibody | BS60071

CDK3 polyclonal Antibody | BS60071 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2–Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. Cdk3, like Cdk2, is known to be required for the G1–S transition. Proteins involved in cell cycle control have become the subject of increased interest with regard to their potential roles in tumorigenesis. Both Cdk3 and Cdk2 have been mapped to regions of a human chromosome that may be altered in a variety of tumors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CDK3 polyclonal Antibody detects endogenous levels of CDK3 protein.

Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cyclin-dependent kinase 3; Cell division protein kinase 3; CDK3; CDKN3

Immunogen: A synthetic peptide corresponding to residues in Human CDK3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Jak Stat ：IL-6 Receptor Signaling,