CDK6 polyclonal Antibody | BS90283

CDK6 polyclonal Antibody | BS90283 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, mouse, rat

Application: WB ICC IHC

Application Range: WB:1:2,000 ICC:1:200 IHC:1:200

Background: CDK6 protein contains a catalytic core composed of a serine/threonine domain.This protein also contains an ATP-binding pocket, inhibitory and activating phosphorylation sites, a PSTAIRE-like cyclin-binding domain and an activating T-loop motif. CDK6 is involved in a positive feedback loop that activates transcription factors through a reaction cascade. CDK6 is important for the control of G1 to S phase transition. However, in recent years, new evidence proved that the presence of CDK6 is not essential for proliferation in every cell type, the cell cycle has a complex circuitry of regulation and the role of CDK6 might be more important in certain cell types than in others, where CDK4 or CDK2 can act as protein kinases compensating its role.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CDK6 polyclonal Antibody detects endogenous levels of CDK6 protein.

Molecular Weight: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CDK6, CDK 6, CDK6, CDK6, Cell division protein kinase 6, Crk 2, Crk2, Cyclin dependent kinase 6, Cyclin-dependent kinase 6, MGC59692, p40, PLSTIRE, Serine/threonine protein kinase PLSTIRE, Serine/threonine-protein kinase PLSTIRE, STQTL11,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: