CDKN2B Antibody (C-term) [APR03916G]

CDKN2B Antibody (C-term) [APR03916G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CDKN2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the C-terminal region of human CDKN2B.

Cellular Localisation: Cytoplasm. Note=Also found in the nucleus

Molecular Weight: 14722

Clone: Polyclonal

Gene Name: CDKN2B

Gene ID: 1030

Function: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Summary: Tissue Location: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IF, WB, FC, IHC-P

Dilution: IF--1:25 IHC-P--1:250 IHC-P--1:100 FC--1:25 WB--1:2000

Synonyms: Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, MTS-2, p14-INK4b, p15-INK4b, p15INK4B, CDKN2B, MTS2