CEACAM6 polyclonal Antibody | BS60595

CEACAM6 polyclonal Antibody | BS60595 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The CD66 (carcinoembryonic antigen, CEA, Biliary glycoprotein I, BGP-1, CECAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues . CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue . The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. . CD66a, CD66b, CD66c, CD66d, CD66e and CD66f are the best characterized CD66 antigens, and CD66a-d expression upregulates on the surface of granulocytes upon stimulation . CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CEACAM6 polyclonal Antibody detects endogenous levels of CEACAM6 protein.

Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Carcinoembryonic antigen-related cell; adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD66c; CEACAM6; NCA

Immunogen: A synthetic peptide corresponding to residues in Human CEACAM6

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: