CEBPA Polyclonal Antibody | E-AB-64040

CEBPA Polyclonal Antibody | E-AB-64040 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CEBPA, C/EBP-alpha, CEBP

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Background: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human CEBPA (NP_004355.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 25 kDa/35 kDa/37 kDa/41 kDa

Molecular Weight(Observed): 41 kDa