CELA2A Antibody (C-term) [APR31188G]

CELA2A Antibody (C-term) [APR31188G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human CELA2A.

Cellular Localisation: Secreted.

Molecular Weight: 28888

Clone: Polyclonal

Gene Name: CELA2A (HGNC:24609)

Gene ID: 63036

Function: Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity.

Summary: Tissue Location: Expressed in pancreas. Not detected in keratinocytes (PubMed:10620133) . Detected in exocrine secretions of the pancreas (at protein level) . Also expressed in a small fraction of cells in pancreatic islets, adrenal cortex, intestinal glands and colonic lymphoid follicles (at protein level) (PubMed:31358993) Detected in plasma (PubMed:31358993) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Chymotrypsin-like elastase family member 2A, Elastase-2A, CELA2A, ELA2A