CELF1 Antibody | 19-959

CELF1 Antibody | 19-959 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 108-483 of human CELF1 (NP_941989.1) .

Research Area: Neuroscience

Tested Application: WB

Application: WB: 1:200 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: SH-SY5Y

Positive Control 3: HepG2

Positive Control 4: NIH/3T3

Positive Control 5: HeLa

Positive Control 6: Mouse liver

Molecular Weight: Observed: 52kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB5NAPOR, hNab5CUGBP Elav-like family member 1, 50 kDa nuclear polyadenylated RNA-binding protein, CELF-1, CUG RNA-binding protein, CUG triplet repeat RNA-binding protein 1, CUG-BP- and ETR-3-like factor 1, CUG-BP1, EDEN-BP homolog, RNA-binding protein BRUNOL-2, bruno-like 2, bruno-like protein 2, deadenylation factor CUG-BP, embryo deadenylation element binding protein, embryo deadenylation element-binding protein homolog, nuclear polyadenylated RNA-binding protein, 50-kD

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.