CEP-18770 | 2433

CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.

CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.

2433 | CEP-18770 DataSheet

Alternate Name/Synonyms: [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid

Appearance: Off-white solid

Formulation: N/A

CAS Number: 847499-27-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₈BN₃O₅

Molecular Weight: 413.28

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>70 mg/ml) or EtOH (>70 mg/ml)

Handling: Protect from air and mositure

Country of Origin: USA

Tag Line: A potent proteosome inhibitor

MDL Number: N/A

PubChem CID: 24800541

SMILES: B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O

InChi: InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1

InChi Key: SJFBTAPEPRWNKH-CCKFTAQKSA-N