CEP164 polyclonal Antibody | BS71388

CEP164 polyclonal Antibody | BS71388 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: CEP164 (Centrosomal protein of 164 kDa) is a 1,460 amino acid protein that plays a critical role in G2/M checkpoint and nuclear divisions by maintaining the formation of primary cilia. CEP164 is required for proper phosphorylation of Chk1, Chk2, Histone H2A and RPA and is therefore an essential player in the DNA-damage-activated ATR/ATM signaling cascade. Localized to the centrioles throughout mitosis, CEP164 also is required for the maintenance of genomic stability and chromosomal segregation. There are two isoforms of CEP164 that are produced as a result of alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CEP164 polyclonal Antibody detects endogenous levels of CEP164 protein.

Molecular Weight: ~ 164 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: KIAA1052; NPHP15; Centrosomal protein of 164 kDa

Immunogen: Recombinant protein of human CEP164.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Inflammasonme Signaling,