CEP170 polyclonal Antibody | BS61661

CEP170 polyclonal Antibody | BS61661 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 geneThe product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with the intraflagellar transport protein 81 (IFT81), the SH3-domain containing protein PRAX-1, and is phosphorylated by cyclin dependent kinase 1 (Cdk1) and polo-like kinase 1 (PLK1), and functions in maintaining Microtubule organization, cell morphology and cilium stability.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CEP170 polyclonal Antibody detects endogenous levels of CEP170 protein.

Molecular Weight: ~ 175 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein; CEP170; FAM68A; KAB; KIAA0470

Immunogen: Synthetic peptide, corresponding Human CEP170.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: