CFH polyclonal Antibody | BS6915

CFH polyclonal Antibody | BS6915 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: IHC

Application Range: IHC 1:50 - 1:200

Background: CFH (Complement factor H) is a member of the Regulator of Complement Activation (RCA) gene cluster and a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this CFH have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CFH polyclonal Antibody detects endogenous levels of CFH protein.

Molecular Weight: ~ 139 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Complement factor H; H factor 1; CFH

Immunogen: Recombinant full length Human CFH.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Warburg Effect,Glutamine Metabolism,AMPK Signaling Pathway,