cFMS Receptor Inhibitor II | B3211

cFMS Receptor Inhibitor II (BUN-60856) is a potent cell-permeable and potent CSF1R (Colony stimulating factor 1 receptor) kinase inhibitor (IC50 = 80 nM). It potently inhibits the cFMS-dependent growth of M-NSF-60 cells.

cFMS Receptor Inhibitor II (BUN-60856) is a potent cell-permeable and potent CSF1R (Colony stimulating factor 1 receptor) kinase inhibitor (IC50 = 80 nM). It potently inhibits the cFMS-dependent growth of M-NSF-60 cells.

B3211 | cFMS Receptor Inhibitor II DataSheet

Alternate Name/Synonyms: 4-((3,4-dimethylphenyl)amino)-7-(pyridin-4-yl)quinoline-3-carboxamide,BUN60856

Appearance: Crystalline solid

Formulation:

CAS Number: 959860-85-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₀N₄O

Molecular Weight: 368.44

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Colony stimulating factor 1 receptor kinase inhibitor

MDL Number:

PubChem CID: 25163930

SMILES: CC1=C(C=C(C=C1)NC2=C3C=CC(=CC3=NC=C2C(=O)N)C4=CC=NC=C4)C

InChi: InChI=1S/C23H20N4O/c1-14-3-5-18(11-15(14)2)27-22-19-6-4-17(16-7-9-25-10-8-16)12-21(19)26-13-20(22)23(24)28/h3-13H,1-2H3,(H2,24,28)(H,26,27)

InChi Key: BIICXZWYHQOUEQ-UHFFFAOYSA-N