CGB (D131) polyclonal Antibody | BS1159

CGB (D131) polyclonal Antibody | BS1159 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC: 1:50~1:200

Background: Choriogonadotropin is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a unique β chain and an α chain common to all gonadotropins. The unique β chain confers biological specificity to choriogonadotropin, luteinizing hormone and follicle stimulating hormone. The secreted α subunit maps to human chromosome 6 and the β subunit of choriogonadotropin maps to human chromosome 19. Choriogonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone. Choriogonadotropin is a member of the cystine knot growth-factor superfamily, a group of proteins that contain a distinct arrangement of six cysteine residues and are expressed in placenta. The proper secretion and dimerization of choriogonadotropin depends on the conformation of the cystine knot, although biological activity is independent of this conformation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CGB (D131) polyclonal Antibody detects endogenous levels of Choriogonadotropin subunit beta protein.

Molecular Weight: ~ 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CG beta; CG-beta; CGB 3; CGB 5; CGB 7; CGB; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin subunit beta; Chorionic gonadotrophin chain beta; Chorionic gonadotropin beta 3 subunit; Chorionic gonadotropin beta 3 subunit precursor; Chorionic gonadotropin beta chain; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta subunit; hCGB; Choriogonadotropin β; hCG beta

Immunogen: Synthetic peptide, corresponding to amino acids 101-150 of Human CGB.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Notch Signaling,Nuclear Receptor Signaling,Cell Cycle Control G1 S Checkpoint,DNA Methylation,Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,