CGK733 | B1725

CGK 733 is a potent and selective inhibitor of ATM/ATR with an IC50 value of ~200 nM.

CGK 733 is a potent and selective inhibitor of ATM/ATR with an IC50 value of ~200 nM.

B1725 | CGK733 DataSheet

Alternate Name/Synonyms: CGK733; CGK 733; CGK733; 2,2-diphenyl-N-[2,2,2-trichloro-1-[(4-fluoro-3-nitrophenyl)carbamothioylamino]ethyl]acetamide

Appearance: Solid

Formulation: N/A

CAS Number: 905973-89-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₁₈Cl₃FN₄O₃S

Molecular Weight: 555.84

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective inhibitor of ATM/ATR

MDL Number: MFCD09038682

PubChem CID: 6605258

SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-]

InChi: InChI=1S/C23H18Cl3FN4O3S/c24-23(25,26)21(30-22(35)28-16-11-12-17(27)18(13-16)31(33)34)29-20(32)19(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,19,21H,(H,29,32)(H2,28,30,35)

InChi Key: HLCDNLNLQNYZTK-UHFFFAOYSA-N