CH13L1 polyclonal Antibody | BS60625-B

CH13L1 polyclonal Antibody | BS60625-B | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:2000~1:5000 IHC: 1:50~1:100

Background: YKL-40, also known as Chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein encoded by the CHI3L1 gene . Unlike other members of the chitinase-like protein family, YKL-40 is not an active chitinase. It is produced by activated macrophages, chondrocytes, neutrophils, and synovial cells. It is a pro-inflammatory molecule that contributes to the progression of many inflammatory diseases, including fibrosis, neurodegenerative disease, breast, lung, prostate, liver, bladder, colon, and other types of cancers. Levels of YKL-40 in serum and plasma in patients with various types of tumors have been reported to predict poor prognosis, and in some clinical assays YKL-40 is being used as a predictive biomarker of cancer outcome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CH13L1 polyclonal Antibody detects endogenous levels of CH13L1 protein.

Molecular Weight: ~ 30-40kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Chitinase-3-like protein 1;39 kDa synovial protein;Cartilage glycoprotein 39;CGP-39;GP-39;hCGP-39;YKL-40;CHI3L1

Immunogen: Synthetic peptide, corresponding to Human CH13L1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Autophagy Signaling,