Chemerin, human recombinant | 4002

Chemerin is a chemoattractant expressed in white adipose, liver and lung tissues. Chemerin is a ligand for the G-protein coupled receptor known as ChemR23 (or chemokine-like receptor-1), which is expressed mainly on dendritic cells, macrophages and some adipocytes. Recombinant human Chemerin, produced in E.coli, is a non-glycosylated protein containing 138 amino acids and having a total molecular mass of 16 kDa.

4002 | Chemerin human recombinant DataSheet

Biomolecule/Target: Chemerin

Synonyms: RARRES2; HP10433; TIG2

Alternates names: BMP-12/GDF-7, BMP12/GDF7, BMP 12/GDF 7,

Taglines: A chemoattractant and a ligand for G-protein coupled receptors

NCBI Gene ID #: 151449

NCBI Gene Symbol: BMP12/GDF7

Gene Source: Human

Accession #: BAD07014

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.01 ng/g

Activity (Specifications/test method): N/A

Biological activity: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The ED for this effect is typically 0.2 – 2.5 µg/ml.

Results: 4-20 ng/mL

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 0.2% TFA.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

Amino acid sequence: N/A