CHIR 99021 trihydrochloride | B1199

CHIR99021 trihydrochloride is the hydrochloride salt of the potent and highly selective glycogen synthase kinase-3β (GSK-3β) inhibitor CHIR99021 (Cat. No. 1677).

CHIR99021 trihydrochloride is the hydrochloride salt of the potent and highly selective glycogen synthase kinase-3β (GSK-3β) inhibitor CHIR99021 (Cat. No. 1677).

B1199 | CHIR 99021 trihydrochloride DataSheet

Alternate Name/Synonyms: 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile trihydrochloride; CT99022

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1782235-14-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: HCl

Molecular Formula: C₂₂H₁₈Cl₂N₈. 3HCl

Molecular Weight: 574.72

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~25 mg/ml) or H₂O (>5 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A GSK-3β inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: CC1=CNC(C(C(C2=CC=C(Cl)C=C2Cl)=N3)=CN=C3NCCNC4=NC=C(C#N)C=C4)=N1.[H]Cl.[H]Cl.[H]Cl

InChi: InChI=1S/C22H18Cl2N8.3ClH/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19;;;/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32);3*1H

InChi Key: DSFVSCNMMZRCIA-UHFFFAOYSA-N