Chlorprothixene hydrochloride | B3091

Chlorprothixene is a thioxanthine antipsychotic drug. It is an antagonist of dopamine and histamine receptors with Ki values of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. It also binds to serotonin or 5-hydroxytryptamine (5-HT) receptors with pKi values of 8.3, 8.5 and 9.4 for 5-HT7, 5-HT6 and 5-HT2 respectively.

Chlorprothixene is a thioxanthine antipsychotic drug. It is an antagonist of dopamine and histamine receptors with Ki values of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. It also binds to serotonin or 5-hydroxytryptamine (5-HT) receptors with pKi values of 8.3, 8.5 and 9.4 for 5-HT7, 5-HT6 and 5-HT2 respectively.

B3091 | Chlorprothixene hydrochloride DataSheet

Alternate Name/Synonyms: Minithixen; (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride; (Z)-2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride; Truxal hydrochloride

Appearance: White to light yellow powder

Formulation:

CAS Number: 6469-93-8

Structure Available?: TRUE

Peptide sequence:

Salt Form: TRUE

Molecular Formula: C₁₈H₁₉Cl₂NS

Molecular Weight: 352.32

Cell-Permeable?: True

Purity: ≥ 98%

Solubilities: ~25 mg/ml in ethanol, ~2.5 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A thioxanthine antipsychotic drug

MDL Number: MFCD01941605

PubChem CID: 5282478

SMILES: CN(C)CCC=C1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl

InChi: InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;

InChi Key: YWKRLOSRDGPEJR-KIUKIJHYSA-N