CHMP5 monoclonal Antibody | MB62814

CHMP5 monoclonal Antibody | MB62814 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]) . [supplied by OMIM, Mar

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: charged multivesicular body protein 5

Molecular Weight: 24.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60

Immunogen: Full length human recombinant protein of human CHMP5 (NP_057494) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A