CHRNA9 polyclonal Antibody | BS71392

CHRNA9 polyclonal Antibody | BS71392 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:1000 - 1:4000

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151) . The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151) . In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CHRNA9 polyclonal Antibody detects endogenous levels of CHRNA9 protein.

Molecular Weight: ~ 75 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neuronal acetylcholine receptor subunit alpha-9; Nicotinic acetylcholine receptor subunit alpha-9; NACHR alpha-9; CHRNA9; NACHRA9

Immunogen: Recombinant protein of human CHRNA9.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: