CHRNE Antibody | 13-399

CHRNE Antibody | 13-399 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1) .

Research Area: Neuroscience

Tested Application: WB

Application: WB: 1:1000 - 1:4000

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: Mouse skeletal muscle

Positive Control 3: Rat kidney

Positive Control 4: Rat skeletal muscle

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 45kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.