CI-994 | 1742

Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models.

CI-994 is a cell-permeable, histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 µM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models.

1742 | CI-994 DataSheet

Alternate Name/Synonyms: 4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, Gö 5549, PD 123654

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 112522-64-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₅N₃O₂

Molecular Weight: 269.3

Cell-Permeable?: Yes

Purity: ≥99% by HPLC

Solubilities: DMSO (60 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A HDAC inhibitor

MDL Number: MFCD00866266

PubChem CID: 2746

SMILES: CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N

InChi: InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)

InChi Key: VAZAPHZUAVEOMC-UHFFFAOYSA-N