CID-1067700 | 2688

CID-1067700 is a potent, and competitive, Ras-related GTPase inhibitor. It binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC₅₀ values of 11.2 and 21 nM, respectively

CID-1067700 is a potent, and competitive, Ras-related GTPase inhibitor. It binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC₅₀ values of 11.2 and 21 nM, respectively

2688 | CID-1067700 DataSheet

Alternate Name/Synonyms: 2-(Benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid, 2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid, CID-1067700, CID1067700, SID57578339; ML282

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 314042-01-8

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₈N₂O₄S₂

Molecular Weight: 390.48

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (~ 10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Ras-related GTPase inhibitor

MDL Number: N/A

PubChem CID: 1067700

SMILES: O=C(C1=C(NC(NC(C2=CC=CC=C2)=O)=S)SC3=C1CC(C)(C)OC3)O

InChi: InChI=1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)

InChi Key: ATSWBWHRHAQVFM-UHFFFAOYSA-N