CIRBP polyclonal Antibody | BS6943

CIRBP polyclonal Antibody | BS6943 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: CIRP, also known as CIRBP (cold inducible RNA binding protein) or A18HNRNP, is a 172 amino acid protein that localizes to the nucleus and contains one RRM (RNA recognition motif) domain. Expressed ubiquitously, CIRP is thought to play an essential role in the suppression of cellular proliferation in response to UV irradiation or extreme cold. Human CIRP, which may be involved in the pathogenesis of endometrial carcinoma, shares 95% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding CIRP maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CIRBP polyclonal Antibody detects endogenous levels of CIRBP protein.

Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cold-inducible RNA-binding protein; A18 hnRNP; Glycine-rich RNA-binding protein CIRP; CIRBP; A18HNRNP; CIRP

Immunogen: Recombinant full length Human CIRBP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: