CIT Antibody | 19-127

CIT Antibody | 19-127 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1300 of human CIT (NP_001193928.1) .

Research Area: Cell Cycle, Chemokines & Cytokines, Immunology, Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: HeLa

Positive Control 3: Jurkat

Positive Control 4: Mouse testis

Positive Control 5: Mouse thymus

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 231kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CITK, CRIK, MCPH17, STK21, citron Rho-interacting kinase, citron (rho-interacting, serine/threonine kinase 21) , serine/threonine kinase 21, serine/threonine-protein kinase 21

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.