Citrullinated Fibrinogen Monoclonal Antibody (Clone 10E9.3) | A2316

Fibrinogen is a glycoprotein complex composed of three different polypeptides (?, ?, ?) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.

A2316 | Citrullinated Fibrinogen Monoclonal Antibody (Clone 10E9.3) DataSheet

Antibody Target: Human citrullinated fibrinogen

Target Alternative Name: Fibrinogen Alpha Chain; Fibrinogen, A Alpha Polypeptide; Fib2; FGA; Fibrinogen Beta Chain; Fibrinogen, B Beta Polypeptide; Epididymis Secretory Sperm Binding Protein Li 78p; Beta-Fibrinogen; HEL-S-78p; FGB; Fibrinogen Gamma Chain; Fibrinogen, Gamma Polypeptide; Testicular Tissue Protein Li 70; FGG

Tag Line: A critical factor in blood clotting, inflammation, and rheumatoid arthritis

Category: GM-CSF

Host: Mouse

Isotype: Mouse IgG2b

Species Reactivities: Human

Immunogen Sequence: Human citrullinated fibrinogen

Accession #: P02675

Gene ID: 2244

Appearance: Liquid

Form:

Concentration:

Formulation: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide

Purification: Protein G purification

Application: Western Blotting ELISA

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE