Clarithromycin | B2692

Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin. It inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD).

Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin. It inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD).

B2692 | Clarithromycin DataSheet

Alternate Name/Synonyms: A-56268,TE 031,6-O-methyl-erythromycin,Antibiotic A 56268

Appearance: White to off-white solid

Formulation:

CAS Number: 81103-11-9

Structure Available?: TRUE

Peptide sequence: N/A

Salt Form: FALSE

Molecular Formula: C₃₈H₆₉NO₁₃

Molecular Weight: 747.95

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~ 1 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A semisynthetic macrolide antibiotic

MDL Number: MFCD00865140

PubChem CID: 84029

SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O

InChi: InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

InChi Key: AGOYDEPGAOXOCK-KCBOHYOISA-N