CLASP1 polyclonal Antibody | BS62340

CLASP1 polyclonal Antibody | BS62340 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Members of the CLASP family, including CLASP1, are mammalian microtubule plus-end binding proteins that interact with CLIPs in order to stabilize the microtubule structures in transfected cells. CLASP1 localizes near the distal end of growing spindle microtubules during mitosis and is a component of the outer corona region of kinetochores. CLASP proteins stabilize microtubules by promoting pauses and restricting MT growth. Defects in CLASP1 cause collapse of the spindle, attachment of kinetochores to short microtubules, and other abnormal mitotic behaviors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CLASP1 polyclonal Antibody detects endogenous levels of CLASP1 protein.

Molecular Weight: ~ 169 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CLIP-associating protein 1; Cytoplasmic linker-associated protein 1; Multiple asters homolog 1; Protein Orbit homolog 1; hOrbit1; CLASP1; KIAA0622, MAST1

Immunogen: Synthetic peptide, corresponding to Human CLASP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: