Claudin-9 polyclonal Antibody | BS61303

Claudin-9 polyclonal Antibody | BS61303 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The claudin superfamily consists of many structurally related proteins in humans (1) . These proteins are important structural and functional components of tight junctions in paracellular transport (1,2) . Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1) . Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (3) . Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4) . Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (5) . Claudin-9 is highly similar to claudin-3 (also designated clostridium perfringens enterotoxin receptor) (6) . Claudin-9 is expressed in simian virus (SV) 40-immortalized human corneal epithelial (THCE) cells (7) . The human claudin-9 gene maps to chromosome 16p13.3 (6) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -26°C long term. Avoid freeze-thaw cycles.

Specificity: Claudin-9 polyclonal Antibody detects endogenous levels of Claudin-9 protein.

Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Claudin-9; CLDN9;

Immunogen: A synthetic peptide corresponding to residues in Human Claudin-9.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: