Cleaved-MMP-27 (Y99) polyclonal Antibody | BS7061

Cleaved-MMP-27 (Y99) polyclonal Antibody | BS7061 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cleaved-MMP-27 (Y99) polyclonal Antibody detects endogenous levels of Cleaved-MMP-27 (45 kDa) protein.

Molecular Weight: ~ 45, 59 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Matrix metalloproteinase-27; MMP-27; MMP27; UNQ2503/PRO5992

Immunogen: Synthetic peptide, corresponding to amino acids 67-115 of Human Cleaved-MMP-27.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A