CLEC12A Antibody (Center) [APR30538G]

CLEC12A Antibody (Center) [APR30538G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CLEC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human CLEC12A.

Cellular Localisation: Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization

Molecular Weight: 30762

Clone: Polyclonal

Gene Name: CLEC12A

Gene ID: 160364

Function: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

Summary: Tissue Location: Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level) . Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CLL-1, Dendritic cell-associated lectin 2, DCAL-2, Myeloid inhibitory C-type lectin-like receptor, MICL, CLEC12A, CLL1, DCAL2, MICL