CLEC9A Antibody (Center) [APR15502G]

CLEC9A Antibody (Center) [APR15502G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CLEC9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human CLEC9A.

Cellular Localisation: Membrane; Single- pass type II membrane protein

Molecular Weight: 27324

Clone: Polyclonal

Gene Name: CLEC9A

Gene ID: 283420

Function: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Summary: Tissue Location: In peripheral blood highly restricted on the surface of BDCA31 (+) dendritic cells and on a small subset of CD14 (+) and CD16 (-) monocytes.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: C-type lectin domain family 9 member A, CLEC9A