CLIC2 Antibody (Center) [APG02650G]

CLIC2 Antibody (Center) [APG02650G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CLIC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 105-137 amino acids from the Central region of human CLIC2.

Cellular Localisation: Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain

Molecular Weight: 28356

Clone: Polyclonal

Gene Name: CLIC2

Gene ID: 1193

Function: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.

Summary: Tissue Location: Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis Expressed in fetal thymus and kidney.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Chloride intracellular channel protein 2, XAP121, CLIC2