CLIC3 (F56) polyclonal Antibody | BS3832

CLIC3 (F56) polyclonal Antibody | BS3832 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: CLIC3 (chloride intracellular channel protein 3) is a member of the highly conserved family of chloride ion channels (CLICs) that function in both soluble and integral membrane forms. Chloride channels regulate cellular traffic of chloride ions, a critical component of all living cells. They are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLIC3 is found in a variety of tissues but is highly expressed in placenta, brain and heart. CLIC3 predominantly localizes to the nucleus and stimulates chloride ion channel activity when expressed in cells. In addition, CLIC3 interacts with ERK 7 and may play a role in the regulation of cell proliferation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CLIC3 (F56) polyclonal Antibody detects endogenous levels of CLIC3 protein.

Molecular Weight: ~ 27 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Chloride intracellular channel protein 3

Immunogen: Synthetic peptide, corresponding to amino acids 31-80 of Human CLIC3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: