CLIP2 polyclonal Antibody | BS61639

CLIP2 polyclonal Antibody | BS61639 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Williams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems, dysmorphic features,mental retardation or learning difficulties and several typical behavioral and neurological abnormalities. In Williams Syndrome patients,a heterozygous deletion is present in a region on chromosome 7q11.23 (the Williams Syndrome critical region), which spans approximately 20 genes. This region comprises the CYLN2 gene, which encodes the cytoplasmic linker protein of (CLIP-115) . CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain. Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, including mild growth deficiency, brain abnormalities, hippocampal dysfunction and particular deficits in motor coordination.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CLIP2 polyclonal Antibody detects endogenous levels of CLIP2 protein.

Molecular Weight: ~ 115 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CAP-Gly domain-containing linker protein 2; Cytoplasmic linker protein 115; CLIP-115; Cytoplasmic linker protein 2; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndrome chromosomal region 4 protein; CLIP2; CYLN2; KIAA0291; WBSCR3; WBSCR4; WSCR4

Immunogen: Synthetic peptide, corresponding Human CLIP2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: