Clofazimine | B2712

Clofazimine is used as an antileprosy drug. It is used to treat multidrug-resistant tuberculosis. Clofazimine prevents neutrophil motility and lymphocyte transformation. It displays anti-inflammatory effect, which is used to treat discoid lupus erythematosus. Clofazimine specifically inhibits canonical Wnt signaling in a panel of TNBC cells in vitro. Clofazimine also displays immunosuppressive property.

Clofazimine is used as an antileprosy drug. It is used to treat multidrug-resistant tuberculosis. Clofazimine prevents neutrophil motility and lymphocyte transformation. It displays anti-inflammatory effect, which is used to treat discoid lupus erythematosus. Clofazimine specifically inhibits canonical Wnt signaling in a panel of TNBC cells in vitro. Clofazimine also displays immunosuppressive property.

B2712 | Clofazimine DataSheet

Alternate Name/Synonyms: NSC 141046,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine

Appearance: Yellow to Amber to Dark red powder

Formulation:

CAS Number: 2030-63-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₂₂Cl₂N₄

Molecular Weight: 473.4

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: ~ 1 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An antimycobacterial compound

MDL Number: MFCD00056793

PubChem CID: 2794

SMILES: CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl

InChi: InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3

InChi Key: WDQPAMHFFCXSNU-UHFFFAOYSA-N