Clonidine hydrochloride | 2684

Clonidine is an antihypertensive agent that acts as an α2-adrenergic receptor agonist that decreases peripheral vascular resistance by centrally inhibiting sympathetic nerve activity. The antihypertensive effects of clonidine have also been attributed to its agonism of the imidazoline (I1) receptor (Ki = 4-8 nM). Also acts as an mTOR-independent autophagy enhancer.

Clonidine is an antihypertensive agent that acts as an α2-adrenergic receptor agonist that decreases peripheral vascular resistance by centrally inhibiting sympathetic nerve activity. The antihypertensive effects of clonidine have also been attributed to its agonism of the imidazoline (I1) receptor (Ki = 4-8 nM). Also acts as an mTOR-independent autophagy enhancer.

2684 | Clonidine hydrochloride DataSheet

Alternate Name/Synonyms: 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 4205-91-8

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₉Cl₂N₃ · HCl

Molecular Weight: 266.55

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml) or H₂O (>25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An antihypertensive agent and an autophagy inducer

MDL Number: MFCD00036705

PubChem CID: 20179

SMILES: C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl

InChi: InChI=1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H

InChi Key: ZNIFSRGNXRYGHF-UHFFFAOYSA-N