Cloxacillin sodium | B2687

Cloxacillin sodium is a β-lactam antibiotic of penicillin subclass, which inhibits bacterial cell wall synthesis by targeting the proteoglycan synthesis. Cloxacillin has a narrow spectrum of action and is effective against Gram-positive organisms. Cloxacillin binds to S. aureus penicillin-binding protein 1 (PBP1), PBP2, PBP3, and PBP4 (IC50s = 0.04, 0.12, 0.21, and 2.5 µg/ml, respectively). Cloxacillin is resistant to the action of β-lactamase and therefore preferentially used for treatment of Staphylococcal infections.

Cloxacillin sodium is a β-lactam antibiotic of penicillin subclass, which inhibits bacterial cell wall synthesis by targeting the proteoglycan synthesis. Cloxacillin has a narrow spectrum of action and is effective against Gram-positive organisms. Cloxacillin binds to S. aureus penicillin-binding protein 1 (PBP1), PBP2, PBP3, and PBP4 (IC50s = 0.04, 0.12, 0.21, and 2.5 µg/ml, respectively). Cloxacillin is resistant to the action of β-lactamase and therefore preferentially used for treatment of Staphylococcal infections.

B2687 | Cloxacillin sodium DataSheet

Alternate Name/Synonyms: Sodium cloxacillin,(2S,5R,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monosodium salt

Appearance: White to off-white solid

Formulation:

CAS Number: 642-78-4

Structure Available?: TRUE

Peptide sequence: N/A

Salt Form: FALSE

Molecular Formula: C19H17ClN3O5S • Na

Molecular Weight: 457.9

Cell-Permeable?: TRUE

Purity: ≥95%

Solubilities: ~15 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A β-lactam antibiotic

MDL Number: MFCD00063568

PubChem CID: 23675320

SMILES: CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]

InChi: InChI=1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1

InChi Key: SCLZRKVZRBKZCR-SLINCCQESA-M